ea0003p224 | Reproduction | BES2002
Monteiro M
, Cardoso H
, Vargas G
, Pichel F
, Pereira I
, Sergio A
, Santos M
, Bravo F
, Santos C
, Ramos H
The association of hyperandrogenism and insulin resistance is common in several syndromes. The proposed mechanism is the stimulation of ovarian theca cells by insulin to produce testosterone. Weight loss, improves insulin resistance, reduces insulin levels and consequently decreases circulating androgens.Material and methods:Ten female subjects with severe obesity and hyperandrogenism were evaluated before and after weight loss at...